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Updated: 2 hours 41 min ago
Treatment with the bisphosphonate zoledronate did not improve outcomes for women with chemoresistant breast cancer, according to initial results of a phase III clinical trial.
Adding the antibody therapy ramucirumab to the chemotherapy drug docetaxel did not delay disease progression for patients with HER2-negative, advanced breast cancer, according to results of a placebo-controlled, randomized, phase III clinical trial.
Changing chemo not beneficial for metastatic breast cancer patients with elevated circulating tumor cells
For women with metastatic breast cancer who had elevated amounts of circulating tumor cells in their blood after a first line of chemotherapy, switching immediately to a different chemotherapy did not improve overall survival or time to progression, according to the results of a phase III clinical trial.
Future solar cells will be light and mechanically flexible. They will be produced at low costs with the help of printing processes. Scientists aim at developing more efficient materials and new architectures for organic photovoltaic devices. They are working on improving the basic understanding and developing new architectures for semitransparent and non-transparent solar cells and modules.
A particularly aggressive form of leukemia is the acute lymphoblastic leukemia (ALL). It is especially common among children and very difficult to treat. Researchers have now discovered completely new targets for the treatment of blood cancers. Studying the cancer protein STAT5, the scientists found new opportunities for the development of effective anti-cancer drugs.
New discovery on how skin cells form 'bridges' paves the way for advances in wound healing and tissue engineering
Scientists have discovered that outer skin cells are able to unite to form suspended “bridges” during wound healing. The new findings will pave the way for tissue engineering, such as the design of artificial skin, and better wound treatment.
Evidence of mass extinction associated with climate change 375 million years ago discovered in Central Asia
Scientists have found evidence for catastrophic oceanographic events associated with climate change and a mass extinction 375 million years ago that devastated tropical marine ecosystems.
Although researchers have determined the ages of rocks from other planetary bodies, the actual experiments -- like analyzing meteorites and moon rocks -- have always been done on Earth. Now, for the first time, researchers have successfully determined the age of a Martian rock -- with experiments performed on Mars. This work could not only help in understanding the geologic history of Mars but also aid in the search for evidence of ancient life there.
The world seems to be getting more complex every day -- some might say too complex. But what if every interaction, every potential conflict we have is really very simple and easy to understand? Mathematicians have found a mathematical formula demonstrating just that: the dynamics of every escalating conflict human beings find themselves in, from children who won't stop crying to international terrorism, can be explained rather easily.
Researchers are developing a new kind of geothermal power plant that will lock away unwanted carbon dioxide underground -- and use it as a tool to boost electric power generation by at least 10 times compared to existing geothermal energy approaches.
New research examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.
In a study of African-American men, researchers found that boys who grew up in two-parent homes were less likely to have high blood pressure as adults compared to those raised by a single parent. This is the first study of an African-American population to document an association between childhood family living arrangements and blood pressure.
The Santa Ana River Watershed Basin Study, which addresses water supply and demand projections for the next 50 years and identifies potential climate change impacts to Southern California's Santa Ana River Watershed, has been released. This study is a first of its kind for the predominately urban basin. It encompasses approximately 2,600 square miles in Orange, Riverside and San Bernardino counties and is home to more than 6 million residents.
A Phase I trial of endoxifen, an active metabolite of the cancer drug tamoxifen, indicates that the experimental drug is safe, with early evidence for anti-tumor activity, a study has found. The findings indicate that Z-endoxifen may provide a new and better treatment for some women with estrogen positive breast cancer and, in particular, for those women who do not respond to tamoxifen and aromatase inhibitors.
Bacteria can evolve rapidly to adapt to environmental change. When the "environment" is the immune response of an infected host, this evolution can turn harmless bacteria into life-threatening pathogens. A new study provides insight into how this happens.
A new type of transistor that could make possible fast and low-power computing devices for energy-constrained applications such as smart sensor networks, implantable medical electronics and ultra-mobile computing is feasible, according researchers. Called a near broken-gap tunnel field effect transistor, the new device uses the quantum mechanical tunneling of electrons through an ultra-thin energy barrier to provide high current at low voltage.
An international team has identified a new disease related to NKH, a finding that resolves previously baffling cases, including the death of a Colorado girl.
Due to improved treatments and technologies, more children than ever are surviving cancer. Unfortunately, about 70 percent of these children experience late effects from their disease and treatment 30 years after their cancer diagnosis, which researchers say significantly impact their quality of life.
Bonefish, sometimes called the gray ghost, are among the most elusive and highly prized quarry of recreational anglers in the Florida Keys, the Bahamas and similar tropical habitats around the world. Now a research team has documented rarely seen pre-spawning behavior in bonefish, which should aid future conservation efforts.
Computer scientists have shown that an important class of artificial intelligence (AI) algorithms could be implemented using chemical reactions. In the long term, they say, such theoretical developments could open the door for "smart drugs" that can automatically detect, diagnose, and treat a variety of diseases using a cocktail of chemicals that can perform AI-type reasoning.