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Brain sleep appeared early in vertebrate evolution. Researchers describe the existence of REM and slow-wave sleep in the Australian dragon, with many common features with mammalian sleep: a phase characterized by low frequency/high amplitude average brain activity and rare and bursty neuronal firing (slow-wave sleep); another characterized by awake-like brain activity and rapid eye movements.
Visitors to Denali National Park and Preserve and Yellowstone National Park were twice as likely to see a wolf when hunting wasn't permitted adjacent to the parks, a new study finds.
Assistive technology -- the use of (frequently modified or customized) equipment to improve the functional capabilities of people with special needs -- is an important therapeutic tool. A new study finds that household utensils modified in relatively simple and cheap ways can increase autonomy and self-esteem and positively impact the quality of life of patients with leprosy.
RNA splicing is a major underlying factor that links mutations to complex traits and diseases, according to an exhaustive analysis of gene expression in whole genome and cell line data. Researchers analyzed how thousands of mutations affect gene regulation in traits such as height, and diseases such as multiple sclerosis. The findings enable accurate functional interpretations of genome-wide association study results.
By administering nicotinamide riboside to elderly mice, researchers restored their organs' ability to regenerate and prolonged their lives. This method has potential for treating a number of degenerative diseases.
In a major breakthrough, scientists have transformed skin cells into heart cells and brain cells using a combination of chemicals. All previous work on cellular reprogramming required adding external genes to the cells, making this accomplishment an unprecedented feat. The research lays the groundwork for one day being able to regenerate lost or damaged cells with pharmaceutical drugs.
Everything you eat or drink affects your intestinal bacteria, and is likely to have an impact on your health. That is the finding of a large-scale study into the effect of food and medicine on the bacterial diversity in the human gut.
Hepatitis C virus hijacks the host's fat metabolism for its own survival, growth, and transport in the human body. A study identifies a host gene involved in the formation of HCV virus particles and helps explain why humans with a rare mutation in the gene have problems with their fat metabolism.
Exposure to Bisphenol-A (BPA) may lead to reduced quality of embryos during reproduction. A new study has shown that BPA could be the cause for decreases in the frequency of implantation, pregnancy and live birth rates in couples seeking in vitro fertilization.
Road crashes are the world's leading cause of preventable death and injury in people under 35, accounting for around 5 million casualties every year. Repeat offenders make a disproportionate contribution to these statistics -- and are known for their poor response to education and prevention efforts. But a better understanding of the subconscious and emotional processes of high-risk drivers could make a difference, according to new research.
The belief that online user ratings are good indicators of product quality is largely an illusion, according to a new study. The analyses show a very low correspondence between average user ratings of products on Amazon.com and product ratings, based on objective tests, found in consumer reports.
Only a few cells in a cancerous tumor are able to break away and spread to other parts of the body, but the curve along the edge of the tumor may play a large role in activating these tumor-seeding cells, according to a new study.
Using a broad spectrum of analytical tools, scientists have shown how sometimes small, often practically imperceptible, structural changes in a key breast cancer receptor are directly linked to regulating molecules and can produce predictable effects in curbing or accelerating cancer growth.
TJP1 protein may identify multiple myeloma patients most likely to benefit from proteasome inhibitors
A gene known as TJP1 (tight junction protein 1) could help determine which multiple myeloma patients would best benefit from proteasome inhibitors such as bortezomib, as well as combination approaches to enhance proteasome inhibitor sensitivity, according to a study.
Flight is one of nature's greatest breakthroughs. It enables escape, dispersion, and exploration. Lacking flight keeps you grounded -- sometimes for a long time even from evolution's perspective. The Madrona Marsh Preserve is a small nature preserve in one of the world's largest metropolitan areas, which has withstood decades of farming, oil exploration, and development pressures. Surprisingly, a treasure of flightless animals survived.
A new report finds a statistically-significant, positive association between high levels of residential radon and the risk of hematologic (blood) cancer in women. Radon is a naturally occurring byproduct of the decay of radium, and is a known human lung carcinogen, the second-leading cause of lung cancer in the United States.
A team of researchers report integrating fiber optic glucose sensors into a microfluidic chip to create portable, high-performance, low-cost devices for measuring glucose levels.
Changes in key genes define four previously unknown conditions within schizophrenia, according to a study. Unlike "big data" genetic studies, which have loosely linked hundreds of genetic changes to schizophrenia but cannot explain varying symptoms, the new study revealed distinct disease versions that may affect large slices of patients and enable precision treatment design, say the authors.
Here's another reason to start saving for that beach house: new research suggests that residents with a view of the water are less stressed.
Parents' beliefs about whether failure is a good or a bad thing guide how their children think about their own intelligence, according to new research. The research indicates that it's parents' responses to failure, and not their beliefs about intelligence, that are ultimately absorbed by their kids.