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Nanodiamonds: Promising use for delivering cancer drug to kill chemoresistant cancer stem cells more effectively
Delivery of Epirubicin by nanodiamonds resulted in a normally lethal dosage of Epirubicin becoming a safe and effective dosage for treatment of liver cancer, researchers report after the conclusion of their study.
Although alcohol is the most important risk factor of alcoholic cirrhosis of the liver, less is known about the significance of different patterns of drinking. Currently scientists believe that cirrhosis is a function of the volume of alcohol consumed irrespective of patterns of drinking. Investigators have now established that alcohol drinking pattern has a significant influence on the risk of cirrhosis and that daily drinking increases that risk compared with drinking less frequently.
A previously unknown phenomenon -- that diseased muscle cells literally eat themselves to death -- has been discovered by researchers. The researchers say this previously unrecognised mechanism could have far reaching effects for the understanding and treatment of diseases including cancers and inflammatory diseases, as well as Duchenne muscular dystrophy.
Workers who participated in an intervention aimed at reducing conflict between work and familial responsibilities slept an hour more each week and reported greater sleep sufficiency than those who did not participate in the intervention, a study shows.
A significant risk for potentially-fatal breathing disruption has been identified when morphine is administered at home after surgery to treat pain in children who undergo tonsillectomy with or without adenoidectomy.
The umami taste could have an important and beneficial role in health, according to research. 'Kokumi' substances, which modify flavor, could improve the taste of low-fat foods, the scientists say.
Young lovers walking down the aisle may dream of long and healthy lives together, but close friends in the wedding party may have a better sense of whether those wishes will come true, suggests new research on personality and longevity.
Researchers have long studied and documented the influence religion has on social groups; however, few have examined the role it plays in education. A new research article examines the relationship between religion and educational attainment in the United States.
Theorists show it may be possible to tune graphene edges by varying heat and force as graphene is fractured. Edge configurations affect graphene's electronic and mechanical properties, which are important for applications.
The "July Effect" -- when newly trained physicians begin their residency at teaching hospitals, potentially increasing the risk of medical errors -- doesn't appear to lengthen surgeries during that month, according to an American study.
Scientists have managed to slow photons in free space for the first time. They have demonstrated that applying a mask to an optical beam to give photons a spatial structure can reduce their speed.
Scientists using ice-penetrating radar have created 3-D maps of the age of the ice within the Greenland Ice Sheet. The new maps will aid future research to understand the impact of climate change on the ice sheet. The Greenland Ice Sheet is the second largest mass of ice on Earth, containing enough water to raise ocean levels by about 20 feet.
The female hormones estrogen and estradiol may help ward off the effects of lead exposure for young girls, explaining why boys, are shown to suffer more often from the cognitive disabilities linked to lead.
To control one's dreams and to live 'out there' what is impossible in real life -- a truly tempting idea. Some persons -- so-called lucid dreamers -- can do this. Researchers have discovered that the brain area which enables self-reflection is larger in lucid dreamers. Thus, lucid dreamers are possibly also more self-reflecting when being awake.
A tool designed to assess what interferes with acute heart failure patients' ability to care for themselves after hospital discharge holds promise for improving patient outcomes and reducing re-admissions to the hospital. The patient survey shed light on the non-medical issues that limit patients' ability to care for themselves.
New information about how antibiotics like azithromycin stop staph infections has been uncovered, including why staph sometimes becomes resistant to drugs. Staphylococcus aureus (familiar to many as the common and sometimes difficult to treat staph infection) is a strain of bacteria that frequently has become resistant to antibiotics, a development that has been challenging for doctors and dangerous for patients with severe infections.
Scientists have long known that sleep, memory and learning are deeply connected but how has remained a mystery. The question is, does the mechanism that promotes sleep also consolidate memory, or do two distinct processes work together? In other words, is memory consolidated during sleep because the brain is quiet or are memory neurons actually putting us to sleep? In a recent paper, researchers make a case for the latter.
Family members, teachers and peers can play different roles in shaping Spanish-speaking children's school readiness and English skills that are vital to children's academic success, research confirms.
A recently discovered family of enzymes can degrade resistant forms of starch, researchers report. Starch is a polysaccharide that is highly prevalent in both food and plants. Determining the way it is broken down by an LPMO now offers potential for utilising this starch in new ways, potentially including the production of biofuels.
A research team estimates that each year about 15 billion cubic feet of natural gas, worth some $90 million, escapes the Boston region's delivery system. The findings have implications for other regions, especially cities that, like Boston, are older and rely on natural gas for a significant and increasing portion of their energy needs. While policymakers have focused on the production end of the natural gas supply chain--wells, off-shore drilling platforms, and processing plants--much less attention has been paid to the downstream gas delivery infrastructure.