Using a broad spectrum of analytical tools, scientists have shown how sometimes small, often practically imperceptible, structural changes in a key breast cancer receptor are directly linked to regulating molecules and can produce predictable effects in curbing or accelerating cancer growth.
This week's superhero movie roundup has everything: Deadpool, scary clowns, and even a Wonder Man cameo. Read on if you want in on the joke. The post Cape Watch: Suicide Squad Might Give the Joker a New Origin Story appeared first on WIRED.
TJP1 protein may identify multiple myeloma patients most likely to benefit from proteasome inhibitors
A gene known as TJP1 (tight junction protein 1) could help determine which multiple myeloma patients would best benefit from proteasome inhibitors such as bortezomib, as well as combination approaches to enhance proteasome inhibitor sensitivity, according to a study.
Flight is one of nature's greatest breakthroughs. It enables escape, dispersion, and exploration. Lacking flight keeps you grounded -- sometimes for a long time even from evolution's perspective. The Madrona Marsh Preserve is a small nature preserve in one of the world's largest metropolitan areas, which has withstood decades of farming, oil exploration, and development pressures. Surprisingly, a treasure of flightless animals survived.
A new report finds a statistically-significant, positive association between high levels of residential radon and the risk of hematologic (blood) cancer in women. Radon is a naturally occurring byproduct of the decay of radium, and is a known human lung carcinogen, the second-leading cause of lung cancer in the United States.
A team of researchers report integrating fiber optic glucose sensors into a microfluidic chip to create portable, high-performance, low-cost devices for measuring glucose levels.
Changes in key genes define four previously unknown conditions within schizophrenia, according to a study. Unlike "big data" genetic studies, which have loosely linked hundreds of genetic changes to schizophrenia but cannot explain varying symptoms, the new study revealed distinct disease versions that may affect large slices of patients and enable precision treatment design, say the authors.
Here's another reason to start saving for that beach house: new research suggests that residents with a view of the water are less stressed.
Parents' beliefs about whether failure is a good or a bad thing guide how their children think about their own intelligence, according to new research. The research indicates that it's parents' responses to failure, and not their beliefs about intelligence, that are ultimately absorbed by their kids.
The risks of commercial marine shipping accidents across Canada's regions have been outlined in a new report, including information for different cargo types. The report highlights gaps in understanding and areas for further research.
Medical researchers have obtained a breakthrough in identifying genes that increase the chance for mothers to have dizygotic twins. Researchers believe the findings represent a significant advance in the identification of key mechanisms controlling ovarian function and provide a greater understanding of female fertility and infertility.
New cancer drugs, taken in pill form, have become dramatically more expensive in their first year on the market compared with drugs launched 15 years ago, calling into question the sustainability of a system that sets high prices at market entry in addition to rapidly increasing those prices over time.
Researchers have identified a key action of a watershed gene critical to bone formation and the evolution of vertebrates. The Sp7 or Osterix gene more than likely emerged from an ancestral gene family about 400 million years ago, expanding the diversity of life and programming the development of bone-secreting osteoblast cells. The closest living relatives to vertebrates, including sea squirts and lampreys, lack bone and an Sp7 gene.
A neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell. The cells in question are neurons and make the neurotransmitter dopamine, whose deficiency is the culprit in the widespread movement disorder Parkinson's disease.
Normally, it takes weeks to repair the cracking or spalling of columns on just one bridge damaged in an earthquake. Now a team of researchers has developed a new process of fixing damaged bridge columns that takes as little as a few days.
Researchers have figured out how some cells do an end-run on replication quality control -- opening the door to developing new cancer-quashing treatments.
A pair of molecular signals controls skin and hair color in mice and humans -- and could be targeted by new drugs to treat skin pigment disorders like vitiligo, according to a new report.
Caregivers whose eyes wander during playtime -- due to distractions such as smartphones or other technology, for example -- may raise children with shorter attention spans, according to a new study.
Age-dependent changes in pancreatic function related to diabetes have been identified by researchers. The research collaboration to procure and analyze human pancreatic tissue from deceased donors illustrates how the organ’s function changes as we age, and could point the way toward new diabetes treatments, say investigators.
An anonymous reader shares an article on Fortune Magazine: The popular Steam computer game network has started accepting bitcoin in a move aimed at making it easier for players in countries like Brazil and China to make payments. Bitcoin transactions will be integrated into game shopping from Steam, which is owned by Valve Software and claims over 100 million users worldwide. Users will be able to use any bitcoin wallet to scan and pay for games or other items without revealing sensitive financial information via software from Bitpay.
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