DNA does not always adopt the form of the double helix which is associated with the genetic code; it can also form intricate folds and act as an enzyme: a deoxyribozyme. Scientists have solved the first three-dimensional structure of this biomolecule that has proved much more flexible than previously thought. Chemists successfully isolated deoxyribozymes over 20 years ago – a DNA with the ability to act as an enzyme. However, until now they had not been able to associate its catalytic activity with the three-dimensional structure that provides such function to this DNA.
Chemists have taken a leap ahead in understanding enzymes used to crack open cellulose easing subsequent fermentation into alcohol. The study can be important for, among other things, the development and production of sustainable biofuels.
Saline groundwater results from seawater intrusion into coastal aquifers, shifting the fresh-saline water interface upward and landward, and replaces fresh groundwater with saline groundwater. The RO process in coastal aquifers will be helpful in restraining seawater intrusion. Other saline groundwater benefits include consistent annual water temperatures, and lower levels of dissolved oxygen, silt density and phytoplankton. The RO desalination process of seawater requires significant energy and large plant area by valuable shorefront property, both of which increase the product water cost.
Scientists have worked out a way to make electric vehicles not just carbon neutral, but carbon negative by demonstrating how the graphite electrodes used in the lithium-ion batteries can be replaced with carbon recovered from the atmosphere.
itwbennett writes: Representative Darrell Issa, a California Republican and former car-alarm entrepreneur, has suggested that the FBI try unlocking mass shooter Syed Rizwan Farook by copying the hard drive and running password attempts until they find the correct password. Bruce Sewell, Apple's senior vice president and general counsel, said during a congressional hearing that, although the company doesn't know the condition of the shooter's iPhone, Issa's approach may work.
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A security researcher reveals radio security flaws in a high-end quadcopter used by police departments that could be used to take it over or crash it. The post Hacker Says He Can Hijack a $35K Police Drone a Mile Away appeared first on WIRED.
An anonymous reader writes: Play, a new peer-to-peer (P2P) site for downloading torrents, is practically impossible to shut down and promises to be the latest technology to revolutionise online downloads. The platform has appeared recently across ZeroNet, a Budapest-based open source site which is looking to offer a home to decentralised platforms which employ Bitcoin-crypto and BitTorrent technologies. As no central server exists, every additional user is a further point of connection inside the network, helping to avoid potential failures. As the first torrent site to appear on the network, Play can be accessed directly through a ZeroNet URL (only available with the tool installed). The site serves magnetic links sourced from RARBG, with which users can download films, series and other media files, in varying qualities. While ZeroNet itself is not an illegal platform, Play is identical to any other P2P download site in that it could face legal challenges over violating copyright.
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Mystery on the marsh: Newly discovered Anglo-Saxon island is one of the most important archaeological finds in decades
The remains of an Anglo-Saxon island have been uncovered in one of the most important archaeological finds in decades.
Researchers are studying the causes of premature aging of neurons in Parkinson’s patients with a defective DJ1 (PARK7) gene. The genetic defect causes changes in the cellular metabolism meaning that neurons are subjected to oxidative stress and an increased immune response in the brain.
The process of aging begins even before we are born, according to an international team of researchers. In a study using rats to model pregnancy and fetal development, the researchers also found that providing mothers with antioxidants during pregnancy meant that their offspring aged more slowly in adulthood.
A solution for long-term preservation of cells and organs for transplant has been uncovered as part of a global alliance to bank organs. After decades of studies, scientists now believe that a breakthrough in preserving body organs for the purpose of saving lives is close at hand.
A majority of patients diagnosed with breast cancer go on to develop symptoms of post-traumatic stress disorder, and in most of these cases the symptoms persist for at least a year, new research indicates.
In recent decades, obesity has become a global problem. The disease goes hand in hand with a dramatic increase in the proportion of body fat. Researchers have now succeeded in inhibiting a protein in mice that hampers activation of the useful “brown fat” in obese mice. When treated with inhibitors against this protein, obese mice exhibited a notable improvement of their glucose metabolism.
Young adults who regularly use marijuana display altered brain activation patterns during social exclusion, research indicates. In a recent study, participants played a computerized game of catch while undergoing a non-invasive brain scan. They recruited 42 young adults (ages 18-25), about half of whom regularly used marijuana. Unknown to the study participants, the other 'players' in the game were computers and were programmed to exclude them for a portion of the game.
In the brain, patterns of neural activity are perfectly balanced. The interplay between activating and inhibitory neurotransmitters ensures that the level of activity stays within the physiological range. During an epileptic attack excitation gains the upper hand resulting in the death of neurons. Researchers have now discovered a key player in a signal transduction cascade, which protects neurons from hyperexcitation-induced cell death. These results open a new direction for the development of novel therapy options.
A design accessory has been created for monitoring the indoor air quality in facilities such as offices and classrooms. It detects carbon dioxide, temperature and humidity, and uses light signals to guide people to healthy space.
Every cell in our bodies has its proper place, but how do they get there? A research group has discovered the mechanism for a mosaic pattern formation of two different cell types. Their discovery has potentially broad applications as a common principle for determining pattern formation in different types of cell.
Researchers have found the Achilles' heel of one of the most aggressive forms of leukemia that affects both children and adults. They have also identified a possible new treatment that exploits this fatal weakness.
One of the world's top particle accelerators has reached a milestone, achieving its 'first turns' -- circulating beams of particles for the first time. Japan's SuperKEKB accelerator is at the forefront of the 'intensity frontier' and is designed to deliver more than 40 times the rate of collisions between particles than its predecessor.
Injections received in the months prior to total knee or total hip replacement surgery may increase the risk for infection and related complications, according to two new studies -- among the largest conducted on this topic.