Hypnotic Video Takes You Tripping Through the World’s Greenhouses

Wired News - Fri, 31/10/2014 - 10:30am

Artist Joe Hamilton created this lovely, disorienting video by filming greenhouses around the world and then layering them with bits of classical landscape paintings he found on the internet.

The post Hypnotic Video Takes You Tripping Through the World’s Greenhouses appeared first on WIRED.


Categories: Science

Stealth DNA-based carbon nanotubes tunnel into cells to deliver targeted drugs

Kurzweil AI - Fri, 31/10/2014 - 10:10am

An artist’s view of a carbon nanotube inserted in a plasma membrane of a cell. The nanotube forms a nanoscale tunnel in the membrane and the image shows a single long strand of DNA passing through that tunnel. (Credit: LLNL)

A team led by the Lawrence Livermore scientists has created a new way to selectively deliver drugs to a specific area in the body using carbon nanotubes (CNTs).

(KurzweilAI reported on October 17 a similar attempt to sneak drugs into cells using a DNA-based drug-delivery system: nanoscale “cocoons” made of DNA target cancer cells, tricking the cells into absorbing the cocoon, which then unleashes anticancer drugs.)

“Many good and efficient drugs that treat diseases of one organ are quite toxic to another,” said Aleksandr Noy, an LLNL biophysicist who led the study and is the senior author on the paper appearing in the Oct. 30 issue of the journal Nature. “This is why delivery to a particular part of the body and only releasing it there is much better.”

The DNA-based carbon nanotubes, dubbed “porins,” tunnel through cell membranes. They simulate ion channels, which are used by cells to transport vital chemicals: the short CNTs  form tiny pores that transport water, protons, small ions, and DNA.

Porins have significant implications for future health care and bioengineering applications, according to the researchers. In addition to delivering drugs to the body, they could serve as a foundation of novel biosensors and DNA sequencing applications, and be used as components of synthetic cells.*

“We found that these nanopores are a promising biomimetic platform for developing cell interfaces, studying transport in biological channels, and creating biosensors,” Noy said. “We are thinking about CNT porins as a first truly versatile synthetic nanopore that can create a range of applications in biology and materials science.”

The team included colleagues at the Molecular Foundry at the Lawrence Berkeley National Laboratory, University of California Merced and Berkeley campuses, and University of Basque Country in Spain.

* The research showed that CNT porins display many characteristic behaviors of natural ion channels: they spontaneously insert into the membranes, switch between metastable conductance states, and display characteristic macromolecule-induced blockades. The team also found that, as in the biological channels, local channel and membrane charges could control the ionic conductance and ion selectivity of the CNT porins.

Abstract of Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes

There is much interest in developing synthetic analogues of biological membrane channels1 with high efficiency and exquisite selectivity for transporting ions and molecules. Bottom-up2 and top-down3 methods can produce nanopores of a size comparable to that of endogenous protein channels, but replicating their affinity and transport properties remains challenging. In principle, carbon nanotubes (CNTs) should be an ideal membrane channel platform: they exhibit excellent transport properties45678 and their narrow hydrophobic inner pores mimic structural motifs typical of biological channels1. Moreover, simulations predict that CNTs with a length comparable to the thickness of a lipid bilayer membrane can self-insert into the membrane910. Functionalized CNTs have indeed been found to penetrate lipid membranes and cell walls1112, and short tubes have been forced into membranes to create sensors13, yet membrane transport applications of short CNTs remain underexplored. Here we show that short CNTs spontaneously insert into lipid bilayers and live cell membranes to form channels that exhibit a unitary conductance of 70–100 picosiemens under physiological conditions. Despite their structural simplicity, these ‘CNT porins’ transport water, protons, small ions and DNA, stochastically switch between metastable conductance substates, and display characteristic macromolecule-induced ionic current blockades. We also show that local channel and membrane charges can control the conductance and ion selectivity of the CNT porins, thereby establishing these nanopores as a promising biomimetic platform for developing cell interfaces, studying transport in biological channels, and creating stochastic sensors.

Categories: Science

Statisticians Study Who Was Helped Most By Obamacare

Slashdot - Fri, 31/10/2014 - 9:25am
HughPickens.com writes We know that about 10 million more people have insurance coverage this year as a result of the Affordable Care Act but until now it has been difficult to say much about who was getting that Obamacare coverage — where they live, their age, their income and other such details. Now Kevin Quealy and Margot Sanger-Katz report in the NYT that a new data set is providing a clearer picture of which people gained health insurance under the Affordable Care Act. The data is the output of a statistical model based on a large survey of adults and shows that the law has done something rather unusual in the American economy this century: It has pushed back against inequality, essentially redistributing income — in the form of health insurance or insurance subsidies — to many of the groups that have fared poorly over the last few decades. The biggest winners from the law include people between the ages of 18 and 34; blacks; Hispanics; and people who live in rural areas. The areas with the largest increases in the health insurance rate, for example, include rural Arkansas and Nevada; southern Texas; large swaths of New Mexico, Kentucky and West Virginia; and much of inland California and Oregon. Despite many Republican voters' disdain for the Affordable Care Act, parts of the country that lean the most heavily Republican (according to 2012 presidential election results) showed significantly more insurance gains than places where voters lean strongly Democratic. That partly reflects underlying rates of insurance. In liberal places, like Massachusetts and Hawaii, previous state policies had made insurance coverage much more widespread, leaving less room for improvement. But the correlation also reflects trends in wealth and poverty. Many of the poorest and most rural states in the country tend to favor Republican politicians.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Swedish Regulator Orders Last "Hold-Out" ISP To Retain Customer Data

Slashdot - Fri, 31/10/2014 - 8:06am
An anonymous reader writes Despite the death of the EU Data Retention Directive in April, and despite the country having taken six years to even begin to obey the ruling, the Swedish government, via its telecoms regulator, has forced ISPs to continue retaining customer data for law enforcement purposes. Now the last ISP retrenching on the issue has been told that it must comply with the edict or face a fine of five million krona ($680,000). While providers all over Europe have rejoiced in not being obliged any longer to provide infrastructure to retain six months of data per customer, Sweden and the United Kingdom alone have insisted on retaining the ruling — particularly surprising in the case of Sweden, since it took six years to begin adhering to the Data Retention Directive after it was made law in 2006. Britain's Data Retention and Investigatory Powers bill, rushed through in July, actually widens the scope of the original EU order.

Read more of this story at Slashdot.








Categories: Science

Planet Hunting to Sky Surveys, Astronomy and Statistics Realign (Op-Ed)

Space.com - Fri, 31/10/2014 - 7:44am
After a century-long hiatus, astrostatistics is bringing astronomy and statistics back together to answer some of the most challenging problems in science.
Categories: Science

Mark Zuckerberg And John Doerr Donate $1M To Expand The Hour Of Code Campaign

Slashdot - Fri, 31/10/2014 - 7:01am
theodp writes Techcrunch reports that Mark Zuckerberg has donated $500K to expand the Hour of Code campaign, which aims to reach 100 million students this year with its learn-to-code tutorials, including its top-featured tutorial starring Zuckerberg (video). Techcrunch adds that Zuckerberg's donation will be matched by fellow tutorial team teacher Bill Gates (video), Microsoft, Reid Hoffman, Salesforce, Google, and others. Zuck and Gates appear to have a sizable captive audience — a Code.org District Partnership Model brochure on the code-or-no-HS-diploma-for-you Chicago Public Schools' website calls for partner districts to "hold a district-wide Hour of Code event each year" for three years.

Read more of this story at Slashdot.








Categories: Science

Mark Zuckerberg And John Doerr Donate $1M To Expand The Hour Of Code Campaign

Slashdot - Fri, 31/10/2014 - 7:01am
theodp writes Techcrunch reports that Mark Zuckerberg has donated $500K to expand the Hour of Code campaign, which aims to reach 100 million students this year with its learn-to-code tutorials, including its top-featured tutorial starring Zuckerberg (video). Techcrunch adds that Zuckerberg's donation will be matched by fellow tutorial team teacher Bill Gates (video), Microsoft, Reid Hoffman, Salesforce, Google, and others. Zuck and Gates appear to have a sizable captive audience — a Code.org District Partnership Model brochure on the code-or-no-HS-diploma-for-you Chicago Public Schools' website calls for partner districts to "hold a district-wide Hour of Code event each year" for three years.

Read more of this story at Slashdot.








Categories: Science

Mark Zuckerberg And John Doerr Donate $1M To Expand The Hour Of Code Campaign

Slashdot - Fri, 31/10/2014 - 7:01am
theodp writes Techcrunch reports that Mark Zuckerberg has donated $500K to expand the Hour of Code campaign, which aims to reach 100 million students this year with its learn-to-code tutorials, including its top-featured tutorial starring Zuckerberg (video). Techcrunch adds that Zuckerberg's donation will be matched by fellow tutorial team teacher Bill Gates (video), Microsoft, Reid Hoffman, Salesforce, Google, and others. Zuck and Gates appear to have a sizable captive audience — a Code.org District Partnership Model brochure on the code-or-no-HS-diploma-for-you Chicago Public Schools' website calls for partner districts to "hold a district-wide Hour of Code event each year" for three years.

Read more of this story at Slashdot.








Categories: Science

Mark Zuckerberg And John Doerr Donate $1M To Expand The Hour Of Code Campaign

Slashdot - Fri, 31/10/2014 - 7:01am
theodp writes Techcrunch reports that Mark Zuckerberg has donated $500K to expand the Hour of Code campaign, which aims to reach 100 million students this year with its learn-to-code tutorials, including its top-featured tutorial starring Zuckerberg (video). Techcrunch adds that Zuckerberg's donation will be matched by fellow tutorial team teacher Bill Gates (video), Microsoft, Reid Hoffman, Salesforce, Google, and others. Zuck and Gates appear to have a sizable captive audience — a Code.org District Partnership Model brochure on the code-or-no-HS-diploma-for-you Chicago Public Schools' website calls for partner districts to "hold a district-wide Hour of Code event each year" for three years.

Read more of this story at Slashdot.








Categories: Science

Mark Zuckerberg And John Doerr Donate $1M To Expand The Hour Of Code Campaign

Slashdot - Fri, 31/10/2014 - 7:01am
theodp writes Techcrunch reports that Mark Zuckerberg has donated $500K to expand the Hour of Code campaign, which aims to reach 100 million students this year with its learn-to-code tutorials, including its top-featured tutorial starring Zuckerberg (video). Techcrunch adds that Zuckerberg's donation will be matched by fellow tutorial team teacher Bill Gates (video), Microsoft, Reid Hoffman, Salesforce, Google, and others. Zuck and Gates appear to have a sizable captive audience — a Code.org District Partnership Model brochure on the code-or-no-HS-diploma-for-you Chicago Public Schools' website calls for partner districts to "hold a district-wide Hour of Code event each year" for three years.

Read more of this story at Slashdot.








Categories: Science

Mark Zuckerberg And John Doerr Donate $1M To Expand The Hour Of Code Campaign

Slashdot - Fri, 31/10/2014 - 7:01am
theodp writes Techcrunch reports that Mark Zuckerberg has donated $500K to expand the Hour of Code campaign, which aims to reach 100 million students this year with its learn-to-code tutorials, including its top-featured tutorial starring Zuckerberg (video). Techcrunch adds that Zuckerberg's donation will be matched by fellow tutorial team teacher Bill Gates (video), Microsoft, Reid Hoffman, Salesforce, Google, and others. Zuck and Gates appear to have a sizable captive audience — a Code.org District Partnership Model brochure on the code-or-no-HS-diploma-for-you Chicago Public Schools' website calls for partner districts to "hold a district-wide Hour of Code event each year" for three years.

Read more of this story at Slashdot.








Categories: Science

Mark Zuckerberg And John Doerr Donate $1M To Expand The Hour Of Code Campaign

Slashdot - Fri, 31/10/2014 - 7:01am
theodp writes Techcrunch reports that Mark Zuckerberg has donated $500K to expand the Hour of Code campaign, which aims to reach 100 million students this year with its learn-to-code tutorials, including its top-featured tutorial starring Zuckerberg (video). Techcrunch adds that Zuckerberg's donation will be matched by fellow tutorial team teacher Bill Gates (video), Microsoft, Reid Hoffman, Salesforce, Google, and others. Zuck and Gates appear to have a sizable captive audience — a Code.org District Partnership Model brochure on the code-or-no-HS-diploma-for-you Chicago Public Schools' website calls for partner districts to "hold a district-wide Hour of Code event each year" for three years.

Read more of this story at Slashdot.








Categories: Science